4U73

HsMetAP(F309M) IN COMPLEX WITH (amino(phenyl)methyl)phosphonic acid

Summary for 4U73

Entry DOI	10.2210/pdb4u73/pdb
Related	4u1b 4u69 4u6c 4u6e 4u6j 4u6w 4u6z 4u70 4u71 4u75 4u76
Descriptor	Methionine aminopeptidase 1, COBALT (II) ION, POTASSIUM ION, ... (5 entities in total)
Functional Keywords	hydrolase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	34782.33
Authors	Arya, T.,Addlagatta, A. (deposition date: 2014-07-30, release date: 2015-03-25, Last modification date: 2024-03-20)
Primary citation	Arya, T.,Reddi, R.,Kishor, C.,Ganji, R.J.,Bhukya, S.,Gumpena, R.,McGowan, S.,Drag, M.,Addlagatta, A. Identification of the Molecular Basis of Inhibitor Selectivity between the Human and Streptococcal Type I Methionine Aminopeptidases J.Med.Chem., 58:2350-2357, 2015 Cited by PubMed: 25699713 DOI: 10.1021/jm501790e PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation