4TQF

Crystal Structure of the C-terminal domain of IFRS bound with 2-(5-bromothienyl)-L-Ala and ATP

Summary for 4TQF

Entry DOI	10.2210/pdb4tqf/pdb
Descriptor	Pyrrolysine--tRNA ligase, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ... (6 entities in total)
Functional Keywords	amino acyl-trna synthetases, archaeal proteins, evolution, molecular, genetic code, substrate specificity, ligase
Biological source	Methanosarcina mazei
Cellular location	Cytoplasm : Q8PWY1
Total number of polymer chains	1
Total formula weight	34639.60
Authors	Nakamura, A.,O'Donoghue, P.,Soll, D. (deposition date: 2014-06-11, release date: 2014-11-12, Last modification date: 2023-09-27)
Primary citation	Guo, L.T.,Wang, Y.S.,Nakamura, A.,Eiler, D.,Kavran, J.M.,Wong, M.,Kiessling, L.L.,Steitz, T.A.,O'Donoghue, P.,Soll, D. Polyspecific pyrrolysyl-tRNA synthetases from directed evolution. Proc.Natl.Acad.Sci.USA, 111:16724-16729, 2014 Cited by PubMed: 25385624 DOI: 10.1073/pnas.1419737111 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7143 Å)

Structure validation