4TOY

Structure of 35O22 Fab, a HIV-1 neutralizing antibody

Summary for 4TOY

• Entry DOI: 10.2210/pdb4toy/pdb
• Descriptor: 35O22 Fab Heavy chain, 35O22 Fab Light chain (3 entities in total)
• Functional Keywords: hiv-1, antibody, fab, neutralizing, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 49472.33

Authors

Pancera, M.,Kwong, P.D. (deposition date: 2014-06-06, release date: 2014-09-03, Last modification date: 2023-09-27)

• Primary citation: Huang, J.,Kang, B.H.,Pancera, M.,Lee, J.H.,Tong, T.,Feng, Y.,Imamichi, H.,Georgiev, I.S.,Chuang, G.Y.,Druz, A.,Doria-Rose, N.A.,Laub, L.,Sliepen, K.,van Gils, M.J.,de la Pena, A.T.,Derking, R.,Klasse, P.J.,Migueles, S.A.,Bailer, R.T.,Alam, M.,Pugach, P.,Haynes, B.F.,Wyatt, R.T.,Sanders, R.W.,Binley, J.M.,Ward, A.B.,Mascola, J.R.,Kwong, P.D.,Connors, M.; Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface.; Nature, 515:138-142, 2014; PubMed: 25186731; DOI: 10.1038/nature13601

Experimental method

X-RAY DIFFRACTION (1.551 Å)