4TKT

Streptomyces platensis isomigrastatin ketosynthase domain MgsF KS6

Summary for 4TKT

• Entry DOI: 10.2210/pdb4tkt/pdb
• Related: 4OPE 4OPF 4OQJ 4QYR 4WKY 4ZDN
• Descriptor: AT-less polyketide synthase, CHLORIDE ION, SULFATE ION, ... (6 entities in total)
• Functional Keywords: structural genomics, psi-biology, midwest center for structural genomics, mcsg, natpro, enzyme discovery for natural product biosynthesis, transferase
• Biological source: Streptomyces platensis subsp. rosaceus
• Total number of polymer chains: 1
• Total formula weight: 67187.25

Authors

Chang, C.,Li, H.,Endres, M.,Bingman, C.A.,Yennamalli, R.,Lohman, J.R.,Ma, M.,Shen, B.,Phillips Jr., G.N.,Joachimiak, A.,Midwest Center for Structural Genomics (MCSG),Enzyme Discovery for Natural Product Biosynthesis (NatPro) (deposition date: 2014-05-27, release date: 2014-06-11, Last modification date: 2023-03-22)

• Primary citation: Lohman, J.R.,Ma, M.,Osipiuk, J.,Nocek, B.,Kim, Y.,Chang, C.,Cuff, M.,Mack, J.,Bigelow, L.,Li, H.,Endres, M.,Babnigg, G.,Joachimiak, A.,Phillips, G.N.,Shen, B.; Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases.; Proc.Natl.Acad.Sci.USA, 112:12693-12698, 2015; PubMed: 26420866; DOI: 10.1073/pnas.1515460112

Experimental method

X-RAY DIFFRACTION (2.4289 Å)