4S27

Crystal structure of Arabidopsis thaliana ThiC with bound aminoimidazole ribonucleotide, 5'-deoxyadenosine, L-methionine, Fe4S4 cluster and Fe

4S27 の概要

• エントリーDOI: 10.2210/pdb4s27/pdb
• 関連するPDBエントリー: 3EPM 3EPN 3EPO 4N7Q 4S25 4S26 4S28 4S29 4S2A
• 分子名称: Phosphomethylpyrimidine synthase, chloroplastic, IRON/SULFUR CLUSTER, 5-AMINOIMIDAZOLE RIBONUCLEOTIDE, ... (9 entities in total)
• 機能のキーワード: alpha-beta barrel, radical sam superfamily, iron-sulfur cluster, thiamin, vitamin b1, vitamin b12, domain swapping, adomet and glutamate mutase, lyase
• 由来する生物種: Arabidopsis thaliana (mouse-ear cress,thale-cress)
• 細胞内の位置: Plastid, chloroplast stroma : O82392
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 65988.91

構造登録者

Fenwick, M.K.,Mehta, A.P.,Zhang, Y.,Abdelwahed, S.,Begley, T.P.,Ealick, S.E. (登録日: 2015-01-19, 公開日: 2015-04-08, 最終更新日: 2023-09-20)

• 主引用文献: Fenwick, M.K.,Mehta, A.P.,Zhang, Y.,Abdelwahed, S.H.,Begley, T.P.,Ealick, S.E.; Non-canonical active site architecture of the radical SAM thiamin pyrimidine synthase.; Nat Commun, 6:6480-6480, ; PubMed: 25813242; DOI: 10.1038/ncomms7480

実験手法

X-RAY DIFFRACTION (1.27 Å)