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4S0Z

Crystal structure of M26V human DJ-1

Summary for 4S0Z
Entry DOI10.2210/pdb4s0z/pdb
Related1P5F 2RK4 3B36
DescriptorProtein DJ-1, 1,2-ETHANEDIOL, ACETATE ION, ... (4 entities in total)
Functional Keywordsdj-1/thij/pfpi superfamily, oxidative stress response, chaperone
Biological sourceHomo sapiens (human)
Cellular locationCell membrane ; Lipid-anchor : Q99497
Total number of polymer chains1
Total formula weight20474.58
Authors
Milkovic, N.M.,Wilson, M.A. (deposition date: 2015-01-07, release date: 2015-08-05, Last modification date: 2023-09-20)
Primary citationMilkovic, N.M.,Catazaro, J.,Lin, J.,Halouska, S.,Kizziah, J.L.,Basiaga, S.,Cerny, R.L.,Powers, R.,Wilson, M.A.
Transient sampling of aggregation-prone conformations causes pathogenic instability of a parkinsonian mutant of DJ-1 at physiological temperature.
Protein Sci., 24:1671-1685, 2015
Cited by
PubMed: 26234586
DOI: 10.1002/pro.2762
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.45 Å)
Structure validation

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