4RZS
Lac repressor engineered to bind sucralose, unliganded tetramer
Summary for 4RZS
Entry DOI | 10.2210/pdb4rzs/pdb |
Descriptor | Lac repressor, GLYCEROL (3 entities in total) |
Functional Keywords | sucralose, laci, lac repressor, lactose operon repressor, protein design, allostery, escherichia coli, transcription |
Biological source | Escherichia coli |
Total number of polymer chains | 4 |
Total formula weight | 163902.33 |
Authors | Arbing, M.A.,Cascio, D.,Kosuri, S.,Church, G.M. (deposition date: 2014-12-24, release date: 2015-12-23, Last modification date: 2024-02-28) |
Primary citation | Taylor, N.D.,Garruss, A.S.,Moretti, R.,Chan, S.,Arbing, M.A.,Cascio, D.,Rogers, J.K.,Isaacs, F.J.,Kosuri, S.,Baker, D.,Fields, S.,Church, G.M.,Raman, S. Engineering an allosteric transcription factor to respond to new ligands. Nat.Methods, 13:177-183, 2016 Cited by PubMed: 26689263DOI: 10.1038/nmeth.3696 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.71 Å) |
Structure validation
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