4RUG

Cyrstal structure of SLIT-ROBO Rho GTPase-activating protein 2 fragment

Summary for 4RUG

Entry DOI	10.2210/pdb4rug/pdb
Related	4RTT
Descriptor	SLIT-ROBO Rho GTPase-activating protein 2 (2 entities in total)
Functional Keywords	srgap2, sh3, ligand binding, robo1, nuclear, plasma membrane, protein binding
Biological source	Homo sapiens (human)
Cellular location	Cell membrane: O75044
Total number of polymer chains	2
Total formula weight	20542.80
Authors	Opatowsky, Y.,Guez-Hadad, J. (deposition date: 2014-11-19, release date: 2015-11-04, Last modification date: 2024-02-28)
Primary citation	Guez-Haddad, J.,Sporny, M.,Sasson, Y.,Gevorkyan-Airapetov, L.,Lahav-Mankovski, N.,Margulies, D.,Radzimanowski, J.,Opatowsky, Y. The Neuronal Migration Factor srGAP2 Achieves Specificity in Ligand Binding through a Two-Component Molecular Mechanism. Structure, 23:1989-2000, 2015 Cited by PubMed: 26365803 DOI: 10.1016/j.str.2015.08.009 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.73 Å)

Structure validation