4RUA

Crystal structure of Y-family DNA polymerase Dpo4 bypassing a MeFapy-dG adduct

Summary for 4RUA

Entry DOI	10.2210/pdb4rua/pdb
Related	4RU9 4RUC
Descriptor	DNA polymerase IV, Nucleic acids Template: TCAT(MF7)GAATCCTTCCCCC, Nucleic acids Primar: GGGGGAAGGATTC, ... (6 entities in total)
Functional Keywords	protein, dna, dna damage, dna-directed dna polymerase, adenosine triphosphate, y-family polymerase, trans-lesion synthesis (tls), dna binding, mefapy-dg lesion bypass, 2, 6-diamino-4-hydroxy n(5)-(methyl)-formamidopyrimidine (mefapy-dg) lesion, transferase-dna complex, transferase/dna
Biological source	Sulfolobus solfataricus P2 More
Cellular location	Cytoplasm : Q97W02
Total number of polymer chains	3
Total formula weight	49147.14
Authors	Patra, A.,Banerjee, S.,Stone, M.P.,Egli, M. (deposition date: 2014-11-18, release date: 2015-08-05, Last modification date: 2023-09-20)
Primary citation	Patra, A.,Banerjee, S.,Johnson Salyard, T.L.,Malik, C.K.,Christov, P.P.,Rizzo, C.J.,Stone, M.P.,Egli, M. Structural Basis for Error-Free Bypass of the 5-N-Methylformamidopyrimidine-dG Lesion by Human DNA Polymerase eta and Sulfolobus solfataricus P2 Polymerase IV. J.Am.Chem.Soc., 137:7011-7014, 2015 Cited by PubMed: 25988947 DOI: 10.1021/jacs.5b02701 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.07 Å)

Structure validation