4RQE

human Seryl-tRNA synthetase dimer complexed with two molecules of tRNAsec

Summary for 4RQE

• Entry DOI: 10.2210/pdb4rqe/pdb
• Related: 4rqf
• Descriptor: Serine--tRNA ligase, cytoplasmic, selenocysteine tRNA, SERINE, ... (4 entities in total)
• Functional Keywords: aminoacyl-trna synthetase, classii aars, aminoacylation, serine, cytosol, ligase-rna complex, ligase/rna
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm: P49591
• Total number of polymer chains: 4
• Total formula weight: 178791.30

Authors

Xie, W.,Wang, C.,Guo, Y.,Tian, Q.,Jia, Q. (deposition date: 2014-11-03, release date: 2015-11-04, Last modification date: 2023-11-08)

• Primary citation: Wang, C.,Guo, Y.,Tian, Q.,Jia, Q.,Gao, Y.,Zhang, Q.,Zhou, C.,Xie, W.; SerRS-tRNASec complex structures reveal mechanism of the first step in selenocysteine biosynthesis.; Nucleic Acids Res., 43:10534-10545, 2015; PubMed: 26433229; DOI: 10.1093/nar/gkv996

Experimental method

X-RAY DIFFRACTION (4 Å)