4RJF

Crystal structure of the human sliding clamp at 2.0 angstrom resolution

Summary for 4RJF

Entry DOI	10.2210/pdb4rjf/pdb
Descriptor	Proliferating cell nuclear antigen, Cyclin-dependent kinase inhibitor 1 (3 entities in total)
Functional Keywords	sliding clamp, processivity factor, p21, dna polymerase, nucleus, replication
Biological source	Homo sapiens (human) More
Cellular location	Nucleus : P12004 Cytoplasm: P38936
Total number of polymer chains	6
Total formula weight	94676.95
Authors	Kroker, A.J.,Bruning, J.B. (deposition date: 2014-10-09, release date: 2015-08-26, Last modification date: 2023-09-20)
Primary citation	Kroker, A.J.,Bruning, J.B. p21 Exploits Residue Tyr151 as a Tether for High-Affinity PCNA Binding. Biochemistry, 54:3483-3493, 2015 Cited by PubMed: 25972089 DOI: 10.1021/acs.biochem.5b00241 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.0072 Å)

Structure validation