4R65

Ternary complex crystal structure of R258A mutant of DNA polymerase Beta

Summary for 4R65

• Entry DOI: 10.2210/pdb4r65/pdb
• Related: 4R63 4R64 4R66
• Descriptor: DNA polymerase beta, DNA (5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), ... (9 entities in total)
• Functional Keywords: dna polymerase beta, conformational change, enzyme mechanism, transferase-dna complex, transferase/dna
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: P06746
• Total number of polymer chains: 4
• Total formula weight: 48380.22

Authors

Batra, V.K.,Beard, W.A.,Wilson, S.H. (deposition date: 2014-08-22, release date: 2014-10-08, Last modification date: 2024-02-28)

• Primary citation: Beard, W.A.,Shock, D.D.,Batra, V.K.,Prasad, R.,Wilson, S.H.; Substrate-induced DNA Polymerase beta Activation.; J.Biol.Chem., 289:31411-31422, 2014; PubMed: 25261471; DOI: 10.1074/jbc.M114.607432

Experimental method

X-RAY DIFFRACTION (1.95 Å)