4QZV

Bat-derived coronavirus HKU4 uses MERS-CoV receptor human CD26 for cell entry

Summary for 4QZV

• Entry DOI: 10.2210/pdb4qzv/pdb
• Related: 4KR0
• Descriptor: Dipeptidyl peptidase 4, Spike protein S1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: 8-bladed beta-propeller domain, alpha/beta hydrolase domain, blades iv and v, cd26 beta-propeller, hydrolase-viral protein complex, hydrolase/viral protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 229455.56

Authors

Gao, F.G.,Wang, Q.H.,Qi, J.X.,Lu, G.W. (deposition date: 2014-07-29, release date: 2014-10-29, Last modification date: 2020-07-29)

• Primary citation: Wang, Q.H.,Qi, J.X.,Yuan, Y.,Xuan, Y.,Han, P.,Wan, Y.,Ji, W.,Li, Y.,Wu, Y.,Wang, J.,Iwamoto, A.,Woo, P.C.,Yuen, K.Y.,Yan, J.,Lu, G.W.,Gao, G.F.; Bat Origins of MERS-CoV Supported by Bat Coronavirus HKU4 Usage of Human Receptor CD26.; Cell Host Microbe, 16:328-337, 2014; PubMed: 25211075; DOI: 10.1016/j.chom.2014.08.009

Experimental method

X-RAY DIFFRACTION (2.592 Å)