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4QV8

yCP beta5-C52F mutant

Summary for 4QV8
Entry DOI10.2210/pdb4qv8/pdb
Related1RYP 4QTR 4QUX 4QUY 4QV0 4QV1 4QV3 4QV4 4QV5 4QV6 4QV7 4QV8 4QV9 4QVL 4QVM 4QVN 4QVP 4QVQ
DescriptorProteasome subunit alpha type-2, Proteasome subunit beta type-4, Proteasome subunit beta type-5, ... (17 entities in total)
Functional Keywordscancer, proteasome, bortezomib, drug resistance, binding analysis, hydrolase
Biological sourceSaccharomyces cerevisiae (Baker's yeast)
More
Cellular locationCytoplasm: P23639 P22141 P30656 P23724 P30657 P38624 P23638 P40303 P32379 P40302 P21242 P21243 P25043 P25451
Total number of polymer chains28
Total formula weight731428.48
Authors
Huber, E.M.,Heinemeyer, W.,Groll, M. (deposition date: 2014-07-14, release date: 2015-02-04, Last modification date: 2023-09-20)
Primary citationHuber, E.M.,Heinemeyer, W.,Groll, M.
Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914.
Structure, 23:407-417, 2015
Cited by
PubMed: 25599643
DOI: 10.1016/j.str.2014.11.019
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.9 Å)
Structure validation

217705

數據於2024-03-27公開中

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