4QTU

Structure of S. cerevisiae Bud23-Trm112 complex involved in formation of m7G1575 on 18S rRNA (SAM bound form)

Summary for 4QTU

Entry DOI	10.2210/pdb4qtu/pdb
Related	4QTM 4QTT
Descriptor	Multifunctional methyltransferase subunit TRM112, Putative methyltransferase BUD23, ZINC ION, ... (6 entities in total)
Functional Keywords	class i, methyltransferase, transferase
Biological source	Saccharomyces cerevisiae S288c (yeast) More
Cellular location	Cytoplasm : P53738 P25627
Total number of polymer chains	4
Total formula weight	78359.51
Authors	Letoquart, J.,Huvelle, E.,Wacheul, L.,Bourgeois, G.,Zorbas, C.,Graille, M.,Heurgue-Hamard, V.,Lafontaine, D.L.J. (deposition date: 2014-07-09, release date: 2014-12-24, Last modification date: 2023-12-06)
Primary citation	Letoquart, J.,Huvelle, E.,Wacheul, L.,Bourgeois, G.,Zorbas, C.,Graille, M.,Heurgue-Hamard, V.,Lafontaine, D.L. Structural and functional studies of Bud23-Trm112 reveal 18S rRNA N7-G1575 methylation occurs on late 40S precursor ribosomes. Proc.Natl.Acad.Sci.USA, 111:E5518-E5526, 2014 Cited by PubMed: 25489090 DOI: 10.1073/pnas.1413089111 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.124 Å)

Structure validation