4QSU

Structure of the bromodomain of human ATPase family AAA domain-containing protein 2 (ATAD2) in complex with thymine

Summary for 4QSU

Entry DOI	10.2210/pdb4qsu/pdb
Related	4QSP 4QSQ 4QSR 4QSS 4QST 4QSV 4QSW 4QSX
Descriptor	ATPase family AAA domain-containing protein 2, SULFATE ION, 1,2-ETHANEDIOL, ... (5 entities in total)
Functional Keywords	structural genomics consortium (sgc), signaling protein, bromodomain, actyl-lysine binding, atpase family aaa domain-containing protein 2, epigenetics
Biological source	Homo sapiens (human)
Cellular location	Nucleus : Q6PL18
Total number of polymer chains	1
Total formula weight	16206.23
Authors	Chaikuad, A.,Felletar, I.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2014-07-06, release date: 2014-07-23, Last modification date: 2023-09-20)
Primary citation	Chaikuad, A.,Petros, A.M.,Fedorov, O.,Xu, J.,Knapp, S. Structure-based approaches towards identification of fragments for the low-druggability ATAD2 bromodomain MedChemComm, 5:1843-1848, 2014 Cited by DOI: 10.1039/C4MD00237G PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation