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4QR9

Crystal structure of two HMGB1 Box A domains cooperating to underwind and kink a DNA

Summary for 4QR9
Entry DOI10.2210/pdb4qr9/pdb
DescriptorHigh mobility group protein B1, DNA (5'-D(*AP*TP*AP*TP*CP*GP*AP*TP*AP*T)-3'), MAGNESIUM ION, ... (4 entities in total)
Functional Keywordshmg-box, hmgb1, box a domain, high mobility group, dna-binding, bend dna, kink dna, architectural factor, minor groove, chromatin, nucleus, dna binding protein
Biological sourceRattus norvegicus (brown rat,rat,rats)
More
Cellular locationNucleus: P63159
Total number of polymer chains6
Total formula weight30095.03
Authors
Sanchez-Giraldo, R.,Acosta-Reyes, F.J.,Malarkey, C.S.,Saperas, N.,Churchill, M.E.A.,Campos, J.L. (deposition date: 2014-06-30, release date: 2015-07-01, Last modification date: 2023-09-20)
Primary citationSanchez-Giraldo, R.,Acosta-Reyes, F.J.,Malarkey, C.S.,Saperas, N.,Churchill, M.E.,Campos, J.L.
Two high-mobility group box domains act together to underwind and kink DNA.
Acta Crystallogr.,Sect.D, 71:1423-1432, 2015
Cited by
PubMed: 26143914
DOI: 10.1107/S1399004715007452
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

217705

건을2024-03-27부터공개중

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