4QOT
Crystal structure of human copper chaperone bound to the platinum ion
Summary for 4QOT
| Entry DOI | 10.2210/pdb4qot/pdb |
| Related | 3IWL 3IWX |
| Descriptor | Copper transport protein ATOX1, PLATINUM (II) ION, SULFATE ION, ... (4 entities in total) |
| Functional Keywords | metal-binding, metal transport, chaperone, platinum, oxaliplatin |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 2 |
| Total formula weight | 15695.76 |
| Authors | Belviso, B.D.,Galliani, A.,Caliandro, R.,Arnesano, F.,Natile, G. (deposition date: 2014-06-20, release date: 2015-06-24, Last modification date: 2023-11-08) |
| Primary citation | Belviso, B.D.,Galliani, A.,Lasorsa, A.,Mirabelli, V.,Caliandro, R.,Arnesano, F.,Natile, G. Oxaliplatin Binding to Human Copper Chaperone Atox1 and Protein Dimerization Inorg.Chem., 55:6563-6573, 2016 Cited by PubMed: 27305454DOI: 10.1021/acs.inorgchem.6b00750 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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