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4Q2Z

Fab fragment of HIV vaccine-elicited CD4bs-directed antibody, GE356, from a non-human primate

Summary for 4Q2Z
Entry DOI10.2210/pdb4q2z/pdb
Related4KTD 4KTE
DescriptorHeavy chain of Fab fragment of HIV vaccine-elicited CD4bs-directed antibody, Light chain of Fab fragment of HIV vaccine-elicited CD4bs-directed antibody (3 entities in total)
Functional Keywordsfab fragment, hiv viral envelope glycoprotein neutralization, immune system
Biological sourceMacaca mulatta
More
Total number of polymer chains4
Total formula weight95830.75
Authors
Navis, M.,Tran, K.,Bale, S.,Phad, G.,Guenaga, J.,Wilson, R.,Soldemo, M.,McKee, K.,Sundling, C.,Mascola, J.,Li, Y.,Wyatt, R.T.,Hedestam, G.B.K. (deposition date: 2014-04-10, release date: 2014-09-17, Last modification date: 2023-09-20)
Primary citationNavis, M.,Tran, K.,Bale, S.,Phad, G.E.,Guenaga, J.,Wilson, R.,Soldemo, M.,McKee, K.,Sundling, C.,Mascola, J.,Li, Y.,Wyatt, R.T.,Karlsson Hedestam, G.B.
HIV-1 Receptor Binding Site-Directed Antibodies Using a VH1-2 Gene Segment Orthologue Are Activated by Env Trimer Immunization.
Plos Pathog., 10:e1004337-e1004337, 2014
Cited by
PubMed: 25166308
DOI: 10.1371/journal.ppat.1004337
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.93 Å)
Structure validation

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