4PZI

Zinc finger region of MLL2 in complex with CpG DNA

Summary for 4PZI

• Entry DOI: 10.2210/pdb4pzi/pdb
• Descriptor: Histone-lysine N-methyltransferase 2B, DNA (5'-D(*GP*CP*CP*AP*CP*CP*GP*GP*TP*GP*GP*C)-3'), ZINC ION, ... (5 entities in total)
• Functional Keywords: zinc finger, dna-binding, structural genomics, structural genomics consortium, sgc, transcription-dna complex, transcription/dna
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus : Q9UMN6
• Total number of polymer chains: 3
• Total formula weight: 15022.70

Authors

Chao, X.,Tempel, W.,Liu, K.,Dong, A.,Bountra, C.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.M.,Min, J.,Structural Genomics Consortium (SGC) (deposition date: 2014-03-31, release date: 2014-06-04, Last modification date: 2024-04-03)

• Primary citation: Xu, C.,Liu, K.,Lei, M.,Yang, A.,Li, Y.,Hughes, T.R.,Min, J.; DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants.; Structure, 26:85-95.e3, 2018; PubMed: 29276034; DOI: 10.1016/j.str.2017.11.022

Experimental method

X-RAY DIFFRACTION (2.15 Å)