4POK

Crystal structures of thioredoxin with mesna at 2.5A resolution

Summary for 4POK

• Entry DOI: 10.2210/pdb4pok/pdb
• Related: 4POL 4POM
• Descriptor: Thioredoxin, 1-THIOETHANESULFONIC ACID (3 entities in total)
• Functional Keywords: oxidoreductase
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: P10599
• Total number of polymer chains: 4
• Total formula weight: 48346.42

Authors

Sridhar, V.,Chie-Leon, B.,Badger, J.,Nienaber, V.L.,Hausheer, F.H. (deposition date: 2014-02-25, release date: 2014-10-29, Last modification date: 2023-09-20)

• Primary citation: Parker, A.R.,Nienaber, V.L.,Petluru, P.N.,Sridhar, V.,Leverett, B.D.,Ayala, P.Y.,Zhao, M.,Chie-Leon, B.,Jair, K.,Kochat, H.,Badger, J.,Hausheer, F.H.; BNP7787 Forms Novel Covalent Adducts on Human Thioredoxin and Modulates Thioredoxin Activity; J Pharmacol Clin Toxicol, 2:1026-, 2014

Experimental method

X-RAY DIFFRACTION (2.52 Å)