4PDJ
Neutron crystal Structure of E.coli Dihydrofolate Reductase complexed with folate and NADP+
Summary for 4PDJ
| Entry DOI | 10.2210/pdb4pdj/pdb |
| Descriptor | Dihydrofolate reductase, MANGANESE (II) ION, DIHYDROFOLIC ACID, ... (5 entities in total) |
| Functional Keywords | alpha beta alpha sandwich, oxidoreductase |
| Biological source | Escherichia coli |
| Total number of polymer chains | 1 |
| Total formula weight | 19318.05 |
| Authors | Wan, Q.,Kovalevsky, A.Y.,Wilson, M.,Langan, P.,Dealwis, C.,Bennett, B. (deposition date: 2014-04-18, release date: 2015-04-15, Last modification date: 2024-04-03) |
| Primary citation | Wan, Q.,Bennett, B.C.,Wilson, M.A.,Kovalevsky, A.,Langan, P.,Howell, E.E.,Dealwis, C. Toward resolving the catalytic mechanism of dihydrofolate reductase using neutron and ultrahigh-resolution X-ray crystallography. Proc.Natl.Acad.Sci.USA, 111:18225-18230, 2014 Cited by PubMed: 25453083DOI: 10.1073/pnas.1415856111 PDB entries with the same primary citation |
| Experimental method | NEUTRON DIFFRACTION (1.994 Å) X-RAY DIFFRACTION (1.599 Å) |
Structure validation
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