4P6Z

Crystal structure of the human BST2 cytoplasmic domain and the HIV-1 Vpu cytoplasmic domain bound to the clathrin adaptor protein complex 1 (AP1) core

Summary for 4P6Z

• Entry DOI: 10.2210/pdb4p6z/pdb
• Descriptor: AP-1 complex subunit gamma-1, AP-1 complex subunit sigma-1A, AP-1 complex subunit mu-1, ... (7 entities in total)
• Functional Keywords: bst2, tetherin, vpu, hiv, clathrin, ap1, antiviral, restriction factor, antagonism, protein transport
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 6
• Total formula weight: 216053.86

Authors

Jia, X.,Xiong, Y. (deposition date: 2014-03-25, release date: 2014-05-21, Last modification date: 2023-12-27)

• Primary citation: Jia, X.,Weber, E.,Tokarev, A.,Lewinski, M.,Rizk, M.,Suarez, M.,Guatelli, J.,Xiong, Y.; Structural basis of HIV-1 Vpu-mediated BST2 antagonism via hijacking of the clathrin adaptor protein complex 1.; Elife, 3:e02362-e02362, 2014; PubMed: 24843023; DOI: 10.7554/eLife.02362

Experimental method

X-RAY DIFFRACTION (3 Å)