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4OUF

Crystal Structure of CBP bromodomain

Summary for 4OUF
Entry DOI10.2210/pdb4ouf/pdb
DescriptorCREB-binding protein, DI(HYDROXYETHYL)ETHER, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywordstransferase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm: Q92793
Total number of polymer chains2
Total formula weight28050.16
Authors
Roy, S.,Das, C.,Tyler, J.K.,Kutateladze, T.G. (deposition date: 2014-02-17, release date: 2014-03-12, Last modification date: 2023-09-20)
Primary citationDas, C.,Roy, S.,Namjoshi, S.,Malarkey, C.S.,Jones, D.N.,Kutateladze, T.G.,Churchill, M.E.,Tyler, J.K.
Binding of the histone chaperone ASF1 to the CBP bromodomain promotes histone acetylation.
Proc.Natl.Acad.Sci.USA, 111:E1072-E1081, 2014
Cited by
PubMed: 24616510
DOI: 10.1073/pnas.1319122111
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.4 Å)
Structure validation

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