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4OMM

Crystal structure of the intertwined dimer of the c-Src tyrosine kinase SH3 domain mutant N113S

Summary for 4OMM
Entry DOI10.2210/pdb4omm/pdb
Related3FJ5 4HVU 4HVV 4HVW 4JZ3 4JZ4
DescriptorProto-oncogene tyrosine-protein kinase Src, TRIETHYLENE GLYCOL, DI(HYDROXYETHYL)ETHER, ... (6 entities in total)
Functional Keywordsbeta-barrel sandwich, kinase, proline rich motifs, transferase
Biological sourceGallus gallus (bantam,chickens)
Cellular locationCell membrane : P00523
Total number of polymer chains1
Total formula weight9232.11
Authors
Camara-Artigas, A.,Bacarizo, J. (deposition date: 2014-01-27, release date: 2015-01-28, Last modification date: 2023-09-20)
Primary citationCamara-Artigas, A.,Bacarizo, J.,Martin-Garcia, J.M.,Neira, J.L.,Andujar-Sanchez, M.,Ortiz-Salmeron, E.
The role of Gutamine 128 of the SH3 domain of the c-Src tyrosine kinase in 3D domain swapping and amyloid formation
To be Published,
Experimental method
X-RAY DIFFRACTION (1.9 Å)
Structure validation

218500

数据于2024-04-17公开中

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