4OH8

Crystal Structure of the human MST1-RASSF5 SARAH heterodimer

Summary for 4OH8

• Entry DOI: 10.2210/pdb4oh8/pdb
• Related: 4OH9
• Descriptor: Serine/threonine-protein kinase 4, Ras association domain-containing protein 5 (3 entities in total)
• Functional Keywords: coiled-coil, sarah domain, homodimerization, heterodomerization, transferase-apoptosis complex, transferase/apoptosis
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm: Q13043 Q8WWW0
• Total number of polymer chains: 2
• Total formula weight: 12639.23

Authors

Hwang, E.,Cheong, H.-K.,Ul Mushtaq, A.,Kim, H.-Y.,Yeo, K.J.,Kim, E.,Lee, W.C.,Hwang, K.Y.,Cheong, C.,Jeon, Y.H. (deposition date: 2014-01-17, release date: 2014-07-23, Last modification date: 2024-02-28)

• Primary citation: Hwang, E.,Cheong, H.K.,Mushtaq, A.U.,Kim, H.Y.,Yeo, K.J.,Kim, E.,Lee, W.C.,Hwang, K.Y.,Cheong, C.,Jeon, Y.H.; Structural basis of the heterodimerization of the MST and RASSF SARAH domains in the Hippo signalling pathway.; Acta Crystallogr.,Sect.D, 70:1944-1953, 2014; PubMed: 25004971; DOI: 10.1107/S139900471400947X

Experimental method

X-RAY DIFFRACTION (2.281 Å)