4OEG

Crystal Structure Analysis of FGF2-Disaccharide (S9I2) complex

Summary for 4OEG

Entry DOI	10.2210/pdb4oeg/pdb
Related	4OEE 4OEF
Descriptor	Fibroblast growth factor 2, 2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-1-O-methyl-2-O-sulfo-alpha-L-idopyranuronic acid (3 entities in total)
Functional Keywords	heparin/heparin sulfate binding, protein binding
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	17939.31
Authors	Li, Y.C.,Hsiao, C.D. (deposition date: 2014-01-13, release date: 2014-07-09, Last modification date: 2023-09-20)
Primary citation	Li, Y.C.,Ho, I.H.,Ku, C.C.,Zhong, Y.Q.,Hu, Y.P.,Chen, Z.G.,Chen, C.Y.,Lin, W.C.,Zulueta, M.M.,Hung, S.C.,Lin, M.G.,Wang, C.C.,Hsiao, C.D. Interactions that influence the binding of synthetic heparan sulfate based disaccharides to fibroblast growth factor-2. Acs Chem.Biol., 9:1712-1717, 2014 Cited by PubMed: 24959968 DOI: 10.1021/cb500298q PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation