4ODX

4E10 germline encoded precursor no.7 in complex with epitope scaffold T117

Summary for 4ODX

• Entry DOI: 10.2210/pdb4odx/pdb
• Descriptor: 4E10 epitope scaffold T117, GEP7 Fv heavy chain, GEP7 Fv light chain (3 entities in total)
• Functional Keywords: hiv, 4e10, gep, germline, antibody, fv, immunoglobulin, 4e10 epitope, immune system
• Biological source: artificial gene; More
• Total number of polymer chains: 6
• Total formula weight: 88693.53

Authors

Finton, K.A.K. (deposition date: 2014-01-10, release date: 2014-10-08)

• Primary citation: Finton, K.A.,Friend, D.,Jaffe, J.,Gewe, M.,Holmes, M.A.,Larman, H.B.,Stuart, A.,Larimore, K.,Greenberg, P.D.,Elledge, S.J.,Stamatatos, L.,Strong, R.K.; Ontogeny of Recognition Specificity and Functionality for the Broadly Neutralizing Anti-HIV Antibody 4E10.; Plos Pathog., 10:e1004403-e1004403, 2014; PubMed: 25254371; DOI: 10.1371/journal.ppat.1004403

Experimental method

X-RAY DIFFRACTION (3.1 Å)