4OCA

Cryatal structure of ArnB K188A complexted with PLP and UDP-Ara4N

Summary for 4OCA

Entry DOI	10.2210/pdb4oca/pdb
Descriptor	UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase, (2R,3R,4S,5S)-3,4-dihydroxy-5-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]tetrahydro-2H-pyr an-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate (3 entities in total)
Functional Keywords	aminotransferase, transferase
Biological source	Salmonella enterica subsp. enterica serovar Typhimurium
Total number of polymer chains	1
Total formula weight	42567.12
Authors	Sousa, M.C.,Lee, M. (deposition date: 2014-01-08, release date: 2014-03-12, Last modification date: 2024-02-28)
Primary citation	Lee, M.,Sousa, M.C. Structural Basis for Substrate Specificity in ArnB. A Key Enzyme in the Polymyxin Resistance Pathway of Gram-Negative Bacteria. Biochemistry, 53:796-805, 2014 Cited by PubMed: 24460375 DOI: 10.1021/bi4015677 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation