4O30

Crystal structure of ATXR5 in complex with histone H3.1 and AdoHcy

Summary for 4O30

Entry DOI	10.2210/pdb4o30/pdb
Descriptor	Histone-lysine N-methyltransferase ATXR6, putative, histone H3.1, S-ADENOSYL-L-HOMOCYSTEINE, ... (6 entities in total)
Functional Keywords	histone methylation, chromatin, epigenetics, trithorax, set domain, lysine methyltransferases, pcna, histone h3, nucleus, transferase
Biological source	Ricinus communis (Castor bean) More
Cellular location	Plastid, chloroplast (By similarity): B9RU15
Total number of polymer chains	4
Total formula weight	58002.07
Authors	Bergamin, E.,Mongeon, V.,Couture, J.F. (deposition date: 2013-12-17, release date: 2014-03-26, Last modification date: 2024-02-28)
Primary citation	Jacob, Y.,Bergamin, E.,Donoghue, M.T.,Mongeon, V.,LeBlanc, C.,Voigt, P.,Underwood, C.J.,Brunzelle, J.S.,Michaels, S.D.,Reinberg, D.,Couture, J.F.,Martienssen, R.A. Selective methylation of histone H3 variant H3.1 regulates heterochromatin replication. Science, 343:1249-1253, 2014 Cited by PubMed: 24626927 DOI: 10.1126/science.1248357 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation