4NZW

Crystal Structure of STK25-MO25 Complex

4NZW の概要

• エントリーDOI: 10.2210/pdb4nzw/pdb
• 分子名称: Calcium-binding protein 39, Serine/threonine-protein kinase 25, 5-[(E)-(5-CHLORO-2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]-N-[2-(DIETHYLAMINO)ETHYL]-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE (3 entities in total)
• 機能のキーワード: scafolding protein, ser/thr protein kinase, transferase activator-transferase complex, transferase activator/transferase
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cytoplasm : Q9Y376 O00506
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 72785.13

構造登録者

Feng, M.,Hao, Q.,Zhou, Z.C. (登録日: 2013-12-13, 公開日: 2014-12-03, 最終更新日: 2023-11-08)

• 主引用文献: Hao, Q.,Feng, M.,Shi, Z.,Li, C.,Chen, M.,Wang, W.,Zhang, M.,Jiao, S.,Zhou, Z.; Structural insights into regulatory mechanisms of MO25-mediated kinase activation.; J.Struct.Biol., 186:224-233, 2014; PubMed: 24746913; DOI: 10.1016/j.jsb.2014.04.005

実験手法

X-RAY DIFFRACTION (3.583 Å)