4NPP

The GLIC-His10 wild-type structure in equilibrium between the open and locally-closed (LC) forms

Summary for 4NPP

Entry DOI	10.2210/pdb4npp/pdb
Related	4NPQ
Descriptor	Proton-gated ion channel, NICKEL (II) ION (2 entities in total)
Functional Keywords	pentameric ligand-gated ion channel, ph-gated, transmembrane, transport protein
Biological source	Gloeobacter violaceus
Cellular location	Cell inner membrane ; Multi- pass membrane protein : Q7NDN8
Total number of polymer chains	5
Total formula weight	189229.99
Authors	Sauguet, L.,Shahsavar, A.,Poitevin, F.,Huon, C.,Menny, A.,Nemecz, A.,Haouz, A.,Changeux, J.P.,Corringer, P.J.,Delarue, M. (deposition date: 2013-11-22, release date: 2013-12-25, Last modification date: 2023-09-20)
Primary citation	Sauguet, L.,Shahsavar, A.,Poitevin, F.,Huon, C.,Menny, A.,Nemecz, A.,Haouz, A.,Changeux, J.P.,Corringer, P.J.,Delarue, M. Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation. Proc.Natl.Acad.Sci.USA, 111:966-971, 2014 Cited by PubMed: 24367074 DOI: 10.1073/pnas.1314997111 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.35 Å)

Structure validation