4NM6

Crystal structure of TET2-DNA complex

Summary for 4NM6

• Entry DOI: 10.2210/pdb4nm6/pdb
• Descriptor: Methylcytosine dioxygenase TET2, 5'-D(*AP*CP*CP*AP*CP*(5CM)P*GP*GP*TP*GP*GP*T)-3', ZINC ION, ... (6 entities in total)
• Functional Keywords: dna hydroxylation, oxidoreductase-dna complex, oxidoreductase/dna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 59208.39

Authors

Hu, L.,Li, Z.,Cheng, J.,Rao, Q.,Gong, W.,Liu, M.,Wang, P.,Xu, Y. (deposition date: 2013-11-14, release date: 2013-12-18, Last modification date: 2024-02-28)

• Primary citation: Hu, L.,Li, Z.,Cheng, J.,Rao, Q.,Gong, W.,Liu, M.,Shi, Y.G.,Zhu, J.,Wang, P.,Xu, Y.; Crystal Structure of TET2-DNA Complex: Insight into TET-Mediated 5mC Oxidation.; Cell(Cambridge,Mass.), 155:1545-1555, 2013; PubMed: 24315485; DOI: 10.1016/j.cell.2013.11.020

Experimental method

X-RAY DIFFRACTION (2.026 Å)