4NJL

Crystal structure of middle east respiratory syndrome coronavirus S2 protein fusion core

Summary for 4NJL

• Entry DOI: 10.2210/pdb4njl/pdb
• Descriptor: S protein, TRIETHYLENE GLYCOL (3 entities in total)
• Functional Keywords: six-helix-bundle, coronavirus, mers-cov, fusion inhibitor, fusion core, viral protein
• Biological source: Middle East respiratory syndrome coronavirus
• Total number of polymer chains: 1
• Total formula weight: 14195.80

Authors

Zhu, Y.,Lu, L.,Qin, L.,Ye, S.,Jiang, S.,Zhang, R. (deposition date: 2013-11-10, release date: 2014-02-19, Last modification date: 2023-09-20)

• Primary citation: Lu, L.,Liu, Q.,Zhu, Y.,Chan, K.H.,Qin, L.,Li, Y.,Wang, Q.,Chan, J.F.,Du, L.,Yu, F.,Ma, C.,Ye, S.,Yuen, K.Y.,Zhang, R.,Jiang, S.; Structure-based discovery of Middle East respiratory syndrome coronavirus fusion inhibitor.; Nat Commun, 5:3067-3067, 2014; PubMed: 24473083; DOI: 10.1038/ncomms4067

Experimental method

X-RAY DIFFRACTION (2.3 Å)