4NCJ

Crystal Structure of Pyrococcus furiosis Rad50 R805E mutation with ADP Beryllium Flouride

Summary for 4NCJ

Entry DOI	10.2210/pdb4ncj/pdb
Related	4NCH 4NCI 4NCK
Descriptor	DNA double-strand break repair Rad50 ATPase, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ... (5 entities in total)
Functional Keywords	adenosine triphosphatase, dna repair, dna binding protein, fungal protein
Biological source	Pyrococcus furiosus More
Total number of polymer chains	4
Total formula weight	156392.19
Authors	Classen, S.,Williams, G.J.,Arvai, A.S.,Williams, R.S. (deposition date: 2013-10-24, release date: 2014-03-05, Last modification date: 2024-02-28)
Primary citation	Deshpande, R.A.,Williams, G.J.,Limbo, O.,Williams, R.S.,Kuhnlein, J.,Lee, J.H.,Classen, S.,Guenther, G.,Russell, P.,Tainer, J.A.,Paull, T.T. ATP-driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signaling. Embo J., 33:482-500, 2014 Cited by PubMed: 24493214 DOI: 10.1002/embj.201386100 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation