4N9G

Crystal Structure of a Computationally Designed RSV-Presenting Epitope Scaffold And Its Elicited Antibody 17HD9

4N9G の概要

• エントリーDOI: 10.2210/pdb4n9g/pdb
• 分子名称: Antibody 17HD9, Heavy Chain, Antibody 17HD9, Light Chain, Epitope Scaffold rsv_1isea_FFL_001_C, ... (4 entities in total)
• 機能のキーワード: antibody, hairpin, epitope scaffold, immune system
• 由来する生物種: Macaca mulatta; 詳細
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 249699.92

構造登録者

Carrico, C.T.D.,Strong, R.K. (登録日: 2013-10-21, 公開日: 2014-02-12, 最終更新日: 2023-09-20)

• 主引用文献: Correia, B.E.,Bates, J.T.,Loomis, R.J.,Baneyx, G.,Carrico, C.,Jardine, J.G.,Rupert, P.,Correnti, C.,Kalyuzhniy, O.,Vittal, V.,Connell, M.J.,Stevens, E.,Schroeter, A.,Chen, M.,Macpherson, S.,Serra, A.M.,Adachi, Y.,Holmes, M.A.,Li, Y.,Klevit, R.E.,Graham, B.S.,Wyatt, R.T.,Baker, D.,Strong, R.K.,Crowe, J.E.,Johnson, P.R.,Schief, W.R.; Proof of principle for epitope-focused vaccine design.; Nature, 507:201-206, 2014; PubMed: 24499818; DOI: 10.1038/nature12966

実験手法

X-RAY DIFFRACTION (2.5 Å)