4MA8

Crystal structure of mouse prion protein complexed with Chlorpromazine

Summary for 4MA8

• Entry DOI: 10.2210/pdb4ma8/pdb
• Related: 4MA7
• Descriptor: Major prion protein, POM1 heavy chain, POM1 light chain, ... (5 entities in total)
• Functional Keywords: immunoglobulin fold, fab, antibody, mouse prion protein, immune system
• Biological source: Mus musculus (mouse); More
• Cellular location: Cell membrane; Lipid-anchor, GPI-anchor (By similarity): P04925
• Total number of polymer chains: 3
• Total formula weight: 60586.52

Authors

Baral, P.K.,Swayampakula, M.,James, M.N.G. (deposition date: 2013-08-15, release date: 2014-01-22, Last modification date: 2023-09-20)

• Primary citation: Baral, P.K.,Swayampakula, M.,Rout, M.K.,Kav, N.N.,Spyracopoulos, L.,Aguzzi, A.,James, M.N.; Structural basis of prion inhibition by phenothiazine compounds.; Structure, 22:291-303, 2014; PubMed: 24373770; DOI: 10.1016/j.str.2013.11.009

Experimental method

X-RAY DIFFRACTION (2.2 Å)