4M8Q

Ontogeny of recognition specificity and functionality for the anti-HIV neutralizing antibody 4E10

Summary for 4M8Q

• Entry DOI: 10.2210/pdb4m8q/pdb
• Related: 4M62
• Descriptor: GEP1 Fv heavy chain, GEP1 Fv light chain, 4E10 epitope scaffold T117 (3 entities in total)
• Functional Keywords: hiv, 4e10, gep, germline, fv, immunoglobulin, antibody, 4e10 epitope, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 88629.48

Authors

Finton, K.A.K. (deposition date: 2013-08-13, release date: 2014-10-08, Last modification date: 2018-03-07)

• Primary citation: Finton, K.A.,Friend, D.,Jaffe, J.,Gewe, M.,Holmes, M.A.,Larman, H.B.,Stuart, A.,Larimore, K.,Greenberg, P.D.,Elledge, S.J.,Stamatatos, L.,Strong, R.K.; Ontogeny of Recognition Specificity and Functionality for the Broadly Neutralizing Anti-HIV Antibody 4E10.; Plos Pathog., 10:e1004403-e1004403, 2014; PubMed: 25254371; DOI: 10.1371/journal.ppat.1004403

Experimental method

X-RAY DIFFRACTION (2.89 Å)