4M6R

Structural and biochemical basis for the inhibition of cell death by APIP, a methionine salvage enzyme

Summary for 4M6R

• Entry DOI: 10.2210/pdb4m6r/pdb
• Descriptor: Methylthioribulose-1-phosphate dehydratase, ZINC ION (3 entities in total)
• Functional Keywords: apip, mtnb, class ii aldolase family, dehydratase, lyase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: Q96GX9
• Total number of polymer chains: 4
• Total formula weight: 101482.82

Authors

Kang, W.,Hong, S.H.,Lee, H.M.,Kim, N.Y.,Lim, Y.C.,Le, L.T.M.,Lim, B.,Kim, H.C.,Kim, T.Y.,Ashida, H.,Yokota, A.,Hah, S.S.,Chun, K.H.,Jung, Y.K.,Yang, J.K. (deposition date: 2013-08-10, release date: 2014-01-29, Last modification date: 2024-03-20)

• Primary citation: Kang, W.,Hong, S.H.,Lee, H.M.,Kim, N.Y.,Lim, Y.C.,Le, L.T.M.,Lim, B.,Kim, H.C.,Kim, T.Y.,Ashida, H.,Yokota, A.,Hah, S.S.,Chun, K.H.,Jung, Y.K.,Yang, J.K.; Structural and biochemical basis for the inhibition of cell death by APIP, a methionine salvage enzyme.; Proc.Natl.Acad.Sci.USA, 111:581-584, 2014; PubMed: 24367089; DOI: 10.1073/pnas.1308768111

Experimental method

X-RAY DIFFRACTION (2 Å)