4M4P

Crystal structure of EPHA4 ectodomain

Summary for 4M4P

• Entry DOI: 10.2210/pdb4m4p/pdb
• Related: 4M4R
• Descriptor: Ephrin type-A receptor 4, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: eph receptor protein kinase, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 58280.97

Authors

Xu, K.,Tsvetkova-Robev, D.,Xu, Y.,Goldgur, Y.,Chan, Y.-P.,Himanen, J.P.,Nikolov, D.B. (deposition date: 2013-08-07, release date: 2013-10-30, Last modification date: 2023-09-20)

• Primary citation: Xu, K.,Tzvetkova-Robev, D.,Xu, Y.,Goldgur, Y.,Chan, Y.P.,Himanen, J.P.,Nikolov, D.B.; Insights into Eph receptor tyrosine kinase activation from crystal structures of the EphA4 ectodomain and its complex with ephrin-A5.; Proc.Natl.Acad.Sci.USA, 110:14634-14639, 2013; PubMed: 23959867; DOI: 10.1073/pnas.1311000110

Experimental method

X-RAY DIFFRACTION (2.081 Å)