4LAD

Crystal Structure of the Ube2g2:RING-G2BR complex

Summary for 4LAD

• Entry DOI: 10.2210/pdb4lad/pdb
• Related: 2LXH 2LXP
• Descriptor: Ubiquitin-conjugating enzyme E2 G2, E3 ubiquitin-protein ligase AMFR, ZINC ION, ... (5 entities in total)
• Functional Keywords: e2:e3 complex, ligase-ligase complex, ligase/ligase
• Biological source: Homo sapiens (human); More
• Cellular location: Endoplasmic reticulum membrane ; Multi-pass membrane protein : Q9UKV5
• Total number of polymer chains: 2
• Total formula weight: 34360.18

Authors

Liang, Y.-H.,Li, J.,Das, R.,Byrd, R.A.,Ji, X. (deposition date: 2013-06-19, release date: 2013-08-28, Last modification date: 2023-09-20)

• Primary citation: Das, R.,Liang, Y.H.,Mariano, J.,Li, J.,Huang, T.,King, A.,Tarasov, S.G.,Weissman, A.M.,Ji, X.,Byrd, R.A.; Allosteric regulation of E2:E3 interactions promote a processive ubiquitination machine.; Embo J., 32:2504-2516, 2013; PubMed: 23942235; DOI: 10.1038/emboj.2013.174

Experimental method

X-RAY DIFFRACTION (2.3 Å)