4L9M

Autoinhibited state of the Ras-specific exchange factor RasGRP1

Summary for 4L9M

• Entry DOI: 10.2210/pdb4l9m/pdb
• Descriptor: RAS guanyl-releasing protein 1, CITRIC ACID, GLYCEROL, ... (5 entities in total)
• Functional Keywords: ras nucleotide exchange factor, signaling protein
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm, cytosol: O95267
• Total number of polymer chains: 1
• Total formula weight: 64627.63

Authors

Iwig, J.S.,Vercoulen, Y.,Das, R.,Barros, T.,Limnander, A.,Che, Y.,Pelton, J.G.,Wemmer, D.E.,Roose, J.P.,Kuriyan, J. (deposition date: 2013-06-18, release date: 2013-08-21, Last modification date: 2023-09-20)

• Primary citation: Iwig, J.S.,Vercoulen, Y.,Das, R.,Barros, T.,Limnander, A.,Che, Y.,Pelton, J.G.,Wemmer, D.E.,Roose, J.P.,Kuriyan, J.; Structural analysis of autoinhibition in the Ras-specific exchange factor RasGRP1.; Elife, 2:e00813-e00813, 2013; PubMed: 23908768; DOI: 10.7554/eLife.00813

Experimental method

X-RAY DIFFRACTION (3 Å)