4KTD

Fab fragment of HIV vaccine-elicited CD4bs-directed antibody, GE136, from non-human primate

Summary for 4KTD

• Entry DOI: 10.2210/pdb4ktd/pdb
• Related: 4KTE
• Descriptor: GE136 Heavy Chain Fab, GE136 Light Chain Fab, SULFATE ION, ... (5 entities in total)
• Functional Keywords: antibody affinity, antibody specificity, vaccine elicited antibodies, fab fragment, aids vaccines, immune system
• Biological source: Macaca mulatta (rhesus macaque); More
• Total number of polymer chains: 2
• Total formula weight: 48477.89

Authors

Poulsen, C.,Tran, K.,Standfield, R.,Wyatt, R.T. (deposition date: 2013-05-20, release date: 2014-02-05, Last modification date: 2017-11-15)

• Primary citation: Tran, K.,Poulsen, C.,Guenaga, J.,de Val Alda, N.,Wilson, R.,Sundling, C.,Li, Y.,Stanfield, R.L.,Wilson, I.A.,Ward, A.B.,Karlsson Hedestam, G.B.,Wyatt, R.T.; Vaccine-elicited primate antibodies use a distinct approach to the HIV-1 primary receptor binding site informing vaccine redesign.; Proc.Natl.Acad.Sci.USA, 111:E738-E747, 2014; PubMed: 24550318; DOI: 10.1073/pnas.1319512111

Experimental method

X-RAY DIFFRACTION (2 Å)