4KSC

Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain

Summary for 4KSC

Entry DOI	10.2210/pdb4ksc/pdb
Related	4KSB 4KSD 4LSG
Descriptor	Multidrug resistance protein 1A (1 entity in total)
Functional Keywords	transporter, atp binding, membrane, membrane protein, transport protein
Biological source	Mus musculus (mouse)
Total number of polymer chains	1
Total formula weight	141877.88
Authors	Ward, A.,Szewczyk, P.,Grimard, V.,Lee, C.-W.,Martinez, L.,Doshi, R.,Caya, A.,Villaluz, M.,Pardon, E.,Cregger, C.,Swartz, D.J.,Falson, P.,Urbatsch, I.,Govaerts, C.,Steyaert, J.,Chang, G. (deposition date: 2013-05-17, release date: 2013-07-31, Last modification date: 2024-02-28)
Primary citation	Ward, A.B.,Szewczyk, P.,Grimard, V.,Lee, C.W.,Martinez, L.,Doshi, R.,Caya, A.,Villaluz, M.,Pardon, E.,Cregger, C.,Swartz, D.J.,Falson, P.G.,Urbatsch, I.L.,Govaerts, C.,Steyaert, J.,Chang, G. Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain. Proc.Natl.Acad.Sci.USA, 110:13386-13391, 2013 Cited by PubMed: 23901103 DOI: 10.1073/pnas.1309275110 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (4 Å)

Structure validation