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4KEH

Crosslinked Crystal Structure of Type II Fatty Synthase Dehydratase, FabA, and Acyl Carrier Protein, AcpP

Summary for 4KEH
Entry DOI10.2210/pdb4keh/pdb
Related1MKA 2K92
DescriptorN-{3-[DIHYDROXY(NONYL)-LAMBDA~4~-SULFANYL]PROPYL}-N~3~-[(2R)-2-HYDROXY-3,3-DIMETHYL-4-(PHOSPHONOOXY)BUTANOYL]-BETA-ALANINAMIDE, Acyl carrier protein, N-{3-[dihydroxy(nonyl)-lambda~4~-sulfanyl]propyl}-N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alaninamide, ... (4 entities in total)
Functional Keywordsfatty acid synthesis, protein-protein complex, dehydratase/isomerase, acyl carrier protein, isomerase-biosynthetic protein complex, isomerase/biosynthetic protein
Biological sourceEscherichia coli
More
Cellular locationCytoplasm: P0A6Q3
Cytoplasm (By similarity): K0BL73
Total number of polymer chains4
Total formula weight55813.48
Authors
Nguyen, C.,Haushalter, R.,Finzel, K.,Leong, J.,Le, B.C.,Burkart, M.,Tsai, S.C. (deposition date: 2013-04-25, release date: 2013-12-25, Last modification date: 2014-01-29)
Primary citationNguyen, C.,Haushalter, R.W.,Lee, D.J.,Markwick, P.R.,Bruegger, J.,Caldara-Festin, G.,Finzel, K.,Jackson, D.R.,Ishikawa, F.,O'Dowd, B.,McCammon, J.A.,Opella, S.J.,Tsai, S.C.,Burkart, M.D.
Trapping the dynamic acyl carrier protein in fatty acid biosynthesis.
Nature, 505:427-431, 2014
Cited by
PubMed: 24362570
DOI: 10.1038/nature12810
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.901 Å)
Structure validation

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