4JA9
Rat PP5 apo
Summary for 4JA9
| Entry DOI | 10.2210/pdb4ja9/pdb |
| Related | 1WAO 4JA7 |
| Descriptor | Serine/threonine-protein phosphatase 5, MAGNESIUM ION (3 entities in total) |
| Functional Keywords | pp5, activation, tau-dephosphorylation, neurodegenerative disease, ser/thr-protein phosphatase domain, tetratricopeptide repeat domain, hsp90, hydrolase |
| Biological source | Rattus norvegicus (brown rat,rat,rats) |
| Cellular location | Nucleus : P53042 |
| Total number of polymer chains | 1 |
| Total formula weight | 55847.85 |
| Authors | Haslbeck, V.,Helmuth, M.,Alte, F.,Popowicz, G.,Schmidt, W.,Weiwad, M.,Fischer, G.,Gemmecker, G.,Sattler, M.,Striggow, F.,Groll, M.,Richter, K. (deposition date: 2013-02-18, release date: 2014-02-19, Last modification date: 2023-09-20) |
| Primary citation | Haslbeck, V.,Drazic, A.,Eckl, J.M.,Alte, F.,Helmuth, M.,Popowicz, G.,Schmidt, W.,Braun, F.,Weiwad, M.,Fischer, G.,Gemmecker, G.,Sattler, M.,Striggow, F.,Groll, M.,Richter, K. Selective activators of protein phosphatase 5 target the auto-inhibitory mechanism. Biosci.Rep., 35:-, 2015 Cited by PubMed: 26182372DOI: 10.1042/BSR20150042 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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