4J8X

X-ray structure of NCP145 with bound chlorido(eta-6-p-cymene)(N-fluorophenyl-2-pyridinecarbothioamide)ruthenium(II)

Summary for 4J8X

• Entry DOI: 10.2210/pdb4j8x/pdb
• Related: 4J8U 4J8W 4J8X
• Descriptor: Histone H3.2, Histone H4, Histone H2A, ... (9 entities in total)
• Functional Keywords: nucleosome, histone, structural protein-dna complex, structural protein/dna
• Biological source: Xenopus laevis (clawed frog,common platanna,platanna); More
• Cellular location: Nucleus: P84233 P62799 P02281; Chromosome . Nucleus : Q6AZJ8
• Total number of polymer chains: 10
• Total formula weight: 199060.04

Authors

Adhireksan, Z.,Davey, C.A. (deposition date: 2013-02-15, release date: 2013-05-08, Last modification date: 2024-02-28)

• Primary citation: Meier, S.M.,Hanif, M.,Adhireksan, Z.,Pichler, V.,Novak, M.,Jirkovsky, E.,Jakupec, M.A.,Arion, V.B.,Davey, C.A.,Keppler, B.K.,Hartinger, C.G.; Novel metal(II) arene 2-pyridinecarbothioamides: a rationale to orally active organometallic anticancer agents; CHEM SCI, 4:1837-1846, 2013; DOI: 10.1039/C3SC22294B

Experimental method

X-RAY DIFFRACTION (2.87 Å)