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4IQ6

Gsk-3beta with inhibitor 6-chloro-N-cyclohexyl-4-(1H-pyrrolo[2,3-b]pyridin-3-yl)pyridin-2-amine

Summary for 4IQ6
Entry DOI10.2210/pdb4iq6/pdb
DescriptorGlycogen synthase kinase-3 beta, 6-chloro-N-cyclohexyl-4-(1H-pyrrolo[2,3-b]pyridin-3-yl)pyridin-2-amine (2 entities in total)
Functional Keywordsprotein kinase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm : P49841
Total number of polymer chains2
Total formula weight95339.27
Authors
Tong, Y.,Stewart, K.D.,Florjancic, A.S.,Harlan, J.E.,Merta, P.J.,Przytulinska, M.,Soni, N.,Swinger, K.S.,Zhu, H.,Johnson, E.F.,Shoemaker, A.R.,Penning, T.D. (deposition date: 2013-01-10, release date: 2013-04-24, Last modification date: 2024-02-28)
Primary citationTong, Y.,Stewart, K.D.,Florjancic, A.S.,Harlan, J.E.,Merta, P.J.,Przytulinska, M.,Soni, N.,Swinger, K.K.,Zhu, H.,Johnson, E.F.,Shoemaker, A.R.,Penning, T.D.
Azaindole-Based Inhibitors of Cdc7 Kinase: Impact of the Pre-DFG Residue, Val 195.
ACS Med Chem Lett, 4:211-215, 2013
Cited by
PubMed: 24900653
DOI: 10.1021/ml300348c
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.12 Å)
Structure validation

217705

數據於2024-03-27公開中

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