4IG7

Crystal structure of Trichinella spiralis UCH37 bound to Ubiquitin vinyl methyl ester

Summary for 4IG7

Entry DOI	10.2210/pdb4ig7/pdb
Related	3IHR
Descriptor	Ubiquitin C-terminal hydrolase 37, Ubiquitin, METHYL 4-AMINOBUTANOATE, ... (4 entities in total)
Functional Keywords	helix-beta-helix sandwich, deubiquitination, ubiquitin c-terminal hydrolase, cytosol, hydrolase-signaling protein complex, hydrolase/signaling protein
Biological source	Trichinella spiralis More
Cellular location	Ubiquitin: Cytoplasm (By similarity): P0CG48
Total number of polymer chains	2
Total formula weight	47447.65
Authors	Das, C.,Kim, M.I.,Morrow, M.E. (deposition date: 2012-12-16, release date: 2013-05-29, Last modification date: 2023-11-15)
Primary citation	Morrow, M.E.,Kim, M.-I.,Ronau, J.A.,Sheedlo, M.J.,White, R.R.,Chaney, J.,Paul, L.N.,Lill, M.A.,Artavanis-Tsakonas, K.,Das, C. Stabilization of an Unusual Salt Bridge in Ubiquitin by the Extra C‑Terminal Domain of the Proteasome-Associated Deubiquitinase UCH37 as a Mechanism of Its Exo Speciﬁcity. Biochemistry, 52:3564-3578, 2013 Cited by PubMed: 23617878 DOI: 10.1021/bi4003106 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.996 Å)

Structure validation