4I6N

Crystal structure of Trichinella spiralis UCH37 catalytic domain bound to Ubiquitin vinyl methyl ester

Summary for 4I6N

Entry DOI	10.2210/pdb4i6n/pdb
Related	3IHR
Descriptor	Ubiquitin carboxyl-hydrolase, Ubiquitin, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ... (6 entities in total)
Functional Keywords	helix-beta-helix sandwich, protein-protein complex, deubiquitination, ubiquitin c-terminal hydrolase, cytosol, hydrolase-signaling protein complex, hydrolase/signaling protein
Biological source	Trichinella spiralis (Trichina worm) More
Cellular location	Ubiquitin: Cytoplasm (By similarity): P0CG48
Total number of polymer chains	4
Total formula weight	70074.88
Authors	Morrow, M.E.,Ronau, J.A.,White, R.R.,Artavanis-Tsakonas, K.,Das, C. (deposition date: 2012-11-29, release date: 2013-05-29, Last modification date: 2023-11-15)
Primary citation	Morrow, M.E.,Kim, M.I.,Ronau, J.A.,Sheedlo, M.J.,White, R.R.,Chaney, J.,Paul, L.N.,Lill, M.A.,Artavanis-Tsakonas, K.,Das, C. Stabilization of an Unusual Salt Bridge in Ubiquitin by the Extra C-Terminal Domain of the Proteasome-Associated Deubiquitinase UCH37 as a Mechanism of Its Exo Specificity. Biochemistry, 52:3564-3578, 2013 Cited by PubMed: 23617878 DOI: 10.1021/bi4003106 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.701 Å)

Structure validation